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In dogs and cats moribund from overwhelmingly severe infections for which antibacterial therapy is available eg, critical pneumonia, pyometritis , depo-medrol may be lifesaving, acting to inhibit the inflammatory reaction, which itself may be lethal; preventing vascular collapse and preserving the integrity of the blood vessels; modifying the patient s reaction to drugs; and preventing or reducing the exudative reaction which often complicates certain infections.

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Musculoskeletal Conditions As with other adrenal steroidsDEPO-MEDROL Sterile Aqueous Suspension has been found useful in alleviating the pain and lameness associated with acute localized arthritic conditions and generalized arthritic conditionsIt has been used successfully to treat rheumatoid arthritistraumatic arthritisosteoarthritisperiostitistendinitissynovitistenosynovitisbursitisand myositis of horsestraumatic arthritisosteoarthritisand generalized arthritic conditions of dogsRemission of musculoskeletal conditions may be permanentor symptoms may recurdepending on the cause and extent of structural degeneration.

MEDROL Tablets like prednisoloneare contraindicated in animals with arrested tuberculosispeptic ulceracute psychosesand Cushingoid syndromeThe presence of diabetesosteoporosischronic psychotic reactionspredisposition to thrombophlebitishypertensioncongestive heart failurerenal insufficiencyand active tuberculosis necessitates carefully controlled useSome of the above conditions occur only rarely in dogs and cats but should be kept in mind.

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